No matter what role they have in the gnosia event, they will be at a general disadvantage for the entirety of the event. For example: game abilities (doctor, guardian angel) could potentially fail at any time during the event. Crew will be more likely to be targeted by gnosia or AC followers. Followers will be be less convincing and will have a harder time deceiving targets. Gnosia themselves may either be less convincing in deception, have a likelihood that their insta-kill ability could fail, or could even find their need to kill amped up and difficult to control.